A Study Comparing Short-course Antifungal Therapy (SCAT) 7 Day vs Standard 14 Day Antifungal Therapy for Uncomplicated Candidemia

Part of paid clinical trials in Augusta, Georgia.

Sponsor
Augusta University
Study ID
NCT06907992
Status
Not Yet Recruiting

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Conditions

  • Candidemia

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Antifungal treatment — DRUG
    Short-course antifungal therapy (7 days) versus standard of care antifungal therapy (14 days)

Study Details

The goal of this clinical trial is to assess whether a seven-day course of standard of care (echinocandin) antifungal therapy is non-inferior to a 14-day course of echinocandin antifungal therapy in patients with uncomplicated candidemia in terms of clinical, mycologic, adverse events and all cause mortality.

Key Dates

Start date
May 1, 2025
Status verified
Apr 2025
Primary completion
May 1, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: 7 Days
    Study participants randomized to the 7 Day group will receive the short-course antifungal therapy for 7 days.
  • Arm: 14 Days
    Study participants randomized to the 14 Day group will receive the standard of care antifungal therapy for 14 days.

Primary Outcome Measure

Eradication of candida from the blood at day 7 or day 14 [ Time Frame: 14 Days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Augusta UniversityAugustaGeorgia30912-

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Augusta University· Augusta, GA

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