UCSF Biobank for Hereditary Cancers and Tumor-Associated Mutations

Part of paid clinical trials in San Francisco, California.

Sponsor
University of California, San Francisco
Study ID
NCT06895681
Status
Not Yet Recruiting

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Conditions

  • Hereditary Cancer
  • Solid Tumor
  • Solid Tumor, Adult
  • Solid Tumor, Unspecified, Adult
  • Somatic Mutation

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Blood Sample — PROCEDURE
    Obtained at the time of non-study related routine blood draw.
  • Tissue Sample — PROCEDURE
    Obtained at the time of non-study related routine biopsy or surgical procedure.
  • Excess fluid Sample — PROCEDURE
    Obtained at the time of non-study related routine biopsy, surgical procedure, paracentesis, or thoracentesis procedure.
  • Medical Chart Review — OTHER
    Demographic, clinical, and pathologic information will be extracted from the medical record

Study Details

This is a non-therapeutic clinical research biorepository protocol designed to obtain, store, and clinically annotate biospecimens from participants with hereditary cancers. Those biospecimens will be used to generate participant-derived tumor models that will serve as a resource to better understand hereditary cancers and develop new efficient therapies.

Key Dates

Start date
Aug 31, 2026
Status verified
Apr 2026
Primary completion
Dec 31, 2035
Completion
Dec 31, 2035

Study Design

Enrollment
50,000 participants (estimated)

Arms

  • Arm: Adults with solid tumor malignancies
    Participants' biospecimen samples (Tissue, Excess fluid (i.e., ascites, pleural effusions, and Blood) will be obtained during non-study, routine medical visits whenever possible, to minimize participant risk. Blood samples will be collected up to 5 times from consenting participants.

Primary Outcome Measure

Develop participant-derived tumor models of hereditary cancers [ Time Frame: Up to 10 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California, San FranciscoSan FranciscoCalifornia94143
[email protected]
877-827-3222
Varun Monga, MBBS (PRINCIPAL_INVESTIGATOR)

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