Evaluation of Plasma Renin Concentrations in Cardiac Surgery
Part of paid clinical trials in Rochester, Minnesota.
- Sponsor
- Mayo Clinic
- Study ID
- NCT06895213
- Status
- Recruiting
Conditions
- Cardiac Surgery With Cardiopulmonary Bypass
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Study Details
The purpose of this research is to learn more about how renin (a blood test) is affected by cardiopulmonary bypass, the heart-lung machine used during open heart surgery. Renin is a protein that may be elevated in response to low blood pressure or situations where organs do not receive sufficient oxygen. Renin may potentially be used as an indicator for specific treatments aimed to increase the blood pressure. This study will evaluate blood samples for renin concentration throughout the course of open heart surgery.
Key Dates
- Start date
- Apr 14, 2025
- Status verified
- May 2026
- Primary completion
- Jul 31, 2026
- Completion
- Jul 31, 2026
Study Design
- Enrollment
- 100 participants (estimated)
Primary Outcome Measure
Plasma renin concentrations [ Time Frame: Up to 24 hours after surgery ]
Central Contacts
- Patrick M Wieruszewski, Pharm.D.507-255-5732
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Mayo Clinic | Rochester | Minnesota | 55905 |
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