A Study of HS-20110 in Participants With Advanced Solid Tumors

Part of paid clinical trials in Tamarac, Florida.

Sponsor
Hansoh BioMedical R&D Company
Study ID
NCT06892379
Phase
PHASE1
Status
Recruiting
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Conditions

  • Solid Tumors

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • HS-20110 (Phase Ia：Dose escalation ) — DRUG
    HS-20110 for IV infusion of various dose strengths administered in 21 day dosing cycles
  • HS-20110 (Phase Ib:Dose expansion ) — DRUG
    The recommended dose from the dose-escalation stage and other potential doses will be further explored

Study Details

This is an open-label, multicenter study to evaluate the safety and tolerability of HS-20110 in participants with advanced solid malignant tumors

Key Dates

Start date
Feb 26, 2025
Status verified
Apr 2026
Primary completion
Dec 31, 2026
Completion
Sep 30, 2027

Study Design

Enrollment
475 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: HS-20110 (Phase Ia：Dose escalation )
  • Experimental: HS-20110 (Phase 1b Dose expansion)

Primary Outcome Measure

Maximum tolerated dose (MTD) or maximum applicable dose (MAD) [ Time Frame: From day 1 to one months after the last dose in Phase 1a ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
BRCR Medical Center INCTamaracFlorida33321
Chintan Gandhi, MD (PRINCIPAL_INVESTIGATOR)
Fort Wayne Medical Oncology and HematologyFort WayneIndiana46804
Sunil Babu (PRINCIPAL_INVESTIGATOR)
Carolina BioOncology InstituteHuntersvilleNorth Carolina28078
980-441-1148
John Powderly (PRINCIPAL_INVESTIGATOR)
The University of Texas MD Anderson Cancer CenterHoustonTexas77030
Siqing Fu, MD (PRINCIPAL_INVESTIGATOR)
NEXT DallasIrvingTexas75039
Michael Song (PRINCIPAL_INVESTIGATOR)
NEXT OncologySan AntonioTexas78229
David Somerhalder (PRINCIPAL_INVESTIGATOR)
NEXT VirginiaFairfaxVirginia22031
Alexander Spira (PRINCIPAL_INVESTIGATOR)

Find similar trials in Tamarac, FL

By research site
BRCR Medical Center INC· Tamarac, FLFort Wayne Medical Oncology and Hematology· Fort Wayne, INCarolina BioOncology Institute· Huntersville, NCThe University of Texas MD Anderson Cancer Center· Houston, TXNEXT Dallas· Irving, TXNEXT Oncology· San Antonio, TX

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