A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT06891560
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Enfortumab Vedotin — DRUG
    intravenously on Days 1, 8 and 15 of a 28-day cycle-dose can be done up to +/-3 days after the scheduled day of administration

Study Details

The purpose of this study is to find out whether enfortumab vedotin is an effective and safe treatment for people with adenoid cystic carcinoma (ACC).

Key Dates

Start date
Mar 31, 2025
Status verified
Mar 2026
Primary completion
Mar 31, 2027
Completion
Mar 31, 2027

Study Design

Enrollment
34 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: Enfortumab Vedotin
    Participants are treated with enfortumab vedotin at the FDA-approved dose and schedule of intravenously on Days 1, 8 and 15 of a 28-day cycle.

Primary Outcome Measure

best overall response rate [ Time Frame: 1 year ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)Basking RidgeNew Jersey07920
Alan Ho, MD. PhD
646-541-7062
Memorial Sloan Kettering Monmouth (All Protocol Activities)MiddletownNew Jersey07748
Alan Ho, MD, PhD
646-541-7062
Memorial Sloan Kettering Bergen (All Protocol Activities)MontvaleNew Jersey07645
Alan Ho, MD, PhD
646-541-7062
Memorial Sloan Kettering Cancer Center Suffolk - Commack (All Protocol Activities)CommackNew York11725
Alan Ho, MD, PhD
646-541-7062
Memorial Sloan Kettering Westchester (All Protocol Activities)HarrisonNew York10604
Alan Ho, MD, PhD
646-541-7062
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New YorkNew York10065
Alan Ho, MD. PhD
646-541-7062
Winston Wong, MD
646-608-4245
Alan Ho, MD, PhD (PRINCIPAL_INVESTIGATOR)
Memorial Sloan Kettering Nassau (All Protocol Activities)UniondaleNew York11553
Alan Ho, MD, PhD
646-541-7062

Find similar trials in Basking Ridge, NJ

By research site
Memorial Sloan Kettering Basking Ridge (All Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (All Protocol Activities)· Middletown, NJMemorial Sloan Kettering Bergen (All Protocol Activities)· Montvale, NJMemorial Sloan Kettering Cancer Center Suffolk - Commack (All Protocol Activities)· Commack, NYMemorial Sloan Kettering Westchester (All Protocol Activities)· Harrison, NYMemorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY

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