Circadian Rhythms in Human Adipose

Part of paid clinical trials in Rochester, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT06891534
Status
Recruiting
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Conditions

  • Feeding Patterns
  • Obesity, Abdominal

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Accepted

Interventions

  • Continuous Feeding — OTHER
    Participants will receive 24-hour continuous feeds through an NG tube
  • Intermittent feeding — OTHER
    Participants will receive 3 boluses of feeding per day at regular meal times through an NG tube to mimic normal meals.

Study Details

The goal of this study is to understand the underlying circadian rhythms in subcutaneous adipose tissue of humans with our without continuous feeding and how these are altered in people who have obesity.

Key Dates

Start date
Jul 1, 2021
Status verified
Apr 2026
Primary completion
Dec 31, 2029
Completion
Dec 31, 2030

Study Design

Enrollment
40 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Normal weight participants
  • Active Comparator: Participants with obesity

Primary Outcome Measure

rhythmicity of circadian clock mRNA in adipose tissue [ Time Frame: 24 hour ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Mayo ClinicRochesterMinnesota55901
Kelli A Lytle, PhD
[email protected]
503-255-1488

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Mayo Clinic· Rochester, MN

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