The RESPLASH Study

Part of paid clinical trials in New Orleans, Louisiana.

Sponsor
Tulane University
Study ID
NCT06880562
Status
Not Yet Recruiting

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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 75 Years
Healthy Volunteers
Not accepted

Interventions

  • Splanchnic Nerve Denervation — DEVICE
    Catheter-based endovascular denervation (CDN) of renal arteries and splanchnic nerves (celiac + SMA) using radiofrequency ablation
  • Renal Denervation Only — DEVICE
    Catheter-based endovascular denervation (CDN) of renal arteries only, without splanchnic nerve denervation

Study Details

To assess the safety and effectiveness of renal artery denervation with subsequent splanchnic nerves denervation via catheter-based radiofrequency ablation in improving blood pressure and glycemic control in patients with resistant hypertension and type 2 diabetes.

Key Dates

Start date
Jun 30, 2026
Status verified
Feb 2026
Primary completion
Jun 30, 2027
Completion
Jun 30, 2027

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Placebo Comparator: CDN of Renal arteries Arm
    Catheter-based endovascular denervation (CDN) of renal arteries only, without splanchnic nerve denervation
  • Experimental: CND of Renal Arteries and Splanchnic Nerves Arm
    Catheter-based endovascular denervation (CDN) of renal arteries and splanchnic nerves (celiac + SMA) using radiofrequency ablation

Primary Outcome Measure

Change in office systolic and diastolic blood pressure [ Time Frame: Baseline, 3 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
East Jefferson General HospitalNew OrleansLouisiana70006
Chris Wang, MS
[email protected]
504-988-3065
Suzanne Bowers, RN, BSN
[email protected]
504-988-2030
Jose Wiley, MD, MPH, FACC, FACP, FSCAI (PRINCIPAL_INVESTIGATOR)

Find similar trials in New Orleans, LA

By condition
Hypertension (high blood pressure)
By specialty
CardiologyHeart disease
By research site
East Jefferson General Hospital· New Orleans, LA

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