Building Research for Intervention Development in Gliosis and Eating Habits

Part of paid clinical trials in Seattle, Washington.

Sponsor
University of Washington
Study ID
NCT06870578
Status
Recruiting
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Conditions

  • Child Obesity
  • Eating
  • Gliosis

Eligibility Criteria

Sex
ALL
Age
9 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Diet modification — OTHER
    In Study 2 only, children will be provided all meals for a 7-day period. Meals will consist of nutritious foods, calories provided will exceed the child's estimated daily caloric need, and children will be asked to consume meals ad libitum.

Study Details

The goal of this study is to 1) use magnetic resonance imaging (MRI) to evaluate the effect of nutritious foods on inflammation in the human hypothalamus of children and 2) assess the feasibility and acceptability of nutritious food feeding intervention strategies in children with overweight or obesity.

Key Dates

Start date
Apr 3, 2025
Status verified
Jun 2025
Primary completion
Jun 30, 2029
Completion
Jun 30, 2029

Study Design

Enrollment
75 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • No Intervention: Focus Group and Child Taste Test (Study 1)
    No intervention is administered. Adult caregivers will participate in a focus group to assess feasibility of a controlled feeding study in children and children will complete a taste-test of a controlled feeding study menu.
  • Experimental: Study-provided food (Study 2)
    Participants will be provided all meals for a 7-day period. For the other 7-days of their enrollment, they will be asked to consume their usual diet.
  • No Intervention: Focus Group (Study 3)
    No intervention is administered. Adult caregivers of children will participate in a focus group to learn from families about participating in research involving feeding studies in children.

Primary Outcome Measure

T2 relaxation time by brain MRI [ Time Frame: 7 days of diet intervention ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of WashingtonSeattleWashington98109
BRIDGE Study
[email protected]
206-616-6360

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By research site
University of Washington· Seattle, WA

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