Cognitive-Sensorimotor Function in Long-COVID

Part of paid clinical trials in Chicago, Illinois.

Sponsor
VA Office of Research and Development
Study ID
NCT06850350
Status
Recruiting
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Conditions

  • Post-acute Sequelae of SARS-CoV-2 Infection

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Study Details

Growing evidence indicates that many people who have chronic post-acute sequelae of SARS-CoV-2 infection (PASC) will experience ongoing neurological and musculoskeletal impairment that can affect gait and balance. Identifying the factors contributing to these impairments and how they influence functional mobility is the first step towards creating effective evaluation and treatment protocols. In this study the investigators will examine cognition, vision, proprioception, muscle strength, gait and balance in persons with and without PASC to understand how PASC may impact functional mobility through a cognitive-sensorimotor lens. Gait and balance will be studied in environments that stress cognitive and sensory abilities. Study outcomes will be critical for the development of evidence-based Veteran Health Administration diagnostic and standard-of-care protocols to address gait and balance dysfunction in Veterans with PASC for restoring their functional mobility and independence.

Key Dates

Start date
Apr 1, 2026
Status verified
May 2026
Primary completion
Dec 31, 2030
Completion
Dec 31, 2030

Study Design

Enrollment
136 participants (estimated)

Arms

  • Arm: Control
    Adults who previously contracted Covid-19 but do not have Long-COVID.
  • Arm: Experimental
    Adults who previously contracted Covid-19 and have Long-COVID.

Primary Outcome Measure

NIH Toolbox Cognition Battery [ Time Frame: During single session of two hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Jesse Brown VA Medical Center, Chicago, ILChicagoIllinois60612
Matthew J Major, PhD
[email protected]
312-569-6166
Karen M Lenehan
[email protected]
(312) 569-6343
Matthew J. Major, PhD (PRINCIPAL_INVESTIGATOR)

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Jesse Brown VA Medical Center, Chicago, IL· Chicago, IL

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