Incidence & Clinical Significance of Osteolysis Following PEEK Suture Anchor Use in Hand & Wrist Surgery

Part of paid clinical trials in Englewood, Colorado.

Sponsor
University of Colorado, Denver
Study ID
NCT06824545
Status
Not Yet Recruiting

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Conditions

  • Osteolysis

Eligibility Criteria

Sex
ALL
Age
18 Years - 99 Years
Healthy Volunteers
Not accepted

Study Details

This prospective observational study evaluates the incidence \& clinical significance of osteolysis following polyetheretherketone (PEEK) suture anchor use in hand \& wrist surgery. Building on a pilot study, it focuses on patients undergoing hand \& wrist surgeries with suture anchor implantation over the past 10 years. Patients are grouped by anchor composition: PEEK, metallic, or bioabsorbable. The investigators hypothesize that PEEK anchors will show significantly greater osteolysis than metallic or bioabsorbable anchors. Furthermore, among all patients with osteolysis, the investigators expect no statistically significant differences in patient-reported outcomes (PROs), post-op complications, or revision surgery rates, regardless of anchor type. Lastly, for patients with ulnar collateral ligament (UCL) thumb injuries, the investigators hypothesize that osteolysis presence will not correlate with increased UCL laxity upon valgus stress testing compared to the nonoperative thumb.

Key Dates

Start date
Jan 1, 2026
Status verified
Sep 2025
Primary completion
Dec 10, 2026
Completion
Dec 10, 2026

Study Design

Enrollment
180 participants (estimated)

Arms

  • Arm: Patients who underwent hand & wrist surgery with suture anchor implantation over the past 10 years.

Primary Outcome Measure

Rates of Osteolysis [ Time Frame: 18 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UCHealth Steadman Hawkins Clinic InvernessEnglewoodColorado80112-

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