Examining Interactions Between PALS and Caregivers

Part of paid clinical trials in University Park, Pennsylvania.

Sponsor
Penn State University
Study ID
NCT06819124
Status
Recruiting
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Conditions

  • Amyotrophic Lateral Sclerosis (ALS)

Eligibility Criteria

Sex
ALL
Age
18 Years - 90 Years
Healthy Volunteers
Accepted

Interventions

  • Structured Communicative Interaction — BEHAVIORAL
    Two interlocutors, one with ALS and their caregiver will work together. Each participant in the pair will view the same set of words on their screens. After one second, one of the words will be highlighted on the speaker's screen, they will say the word in the phrase "Click on the \_\_\_\_ this time", and the listener will click on it. After the listener has made their selection, both participants will receive feedback on trial success.
  • Unstructured communicative interaction — BEHAVIORAL
    Two interlocutors, one with ALS and their caregiver will work together. The pairs will be presented with two different versions of the same picture with eight differences chosen to elicit the same target segments (e.g., "hid", "ship", "net"). These pictures will be modified from the LUCID corpus. In total, pairs will complete four picture sets per session. Pairs will be given 5 minutes for each picture set.

Study Details

The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and their caregivers. The question is, What are the effects of communicative interaction on verbal communication in people with ALS when they interact with their caregivers and does this change over time? Participants will read words and sentences while they are interacting with their caregivers.

Key Dates

Start date
Jan 22, 2025
Status verified
Apr 2026
Primary completion
Feb 28, 2029
Completion
Feb 28, 2029

Study Design

Enrollment
152 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: People with ALS and their caregivers
    People with ALS and their caregivers will participate in structured communicative interaction.

Primary Outcome Measure

Formant frequencies of speech sounds [ Time Frame: two 60 minute sessions ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Speech Core, Pennsylvania State UniversityUniversity ParkPennsylvania16802
Jimin Lee, Ph.D.
[email protected]
814-867-3373

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By research site
Speech Core, Pennsylvania State University· University Park, PA

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