Impact of Depression on Thermoregulation
Part of paid clinical trials in University Park, Pennsylvania.
- Sponsor
- Penn State University
- Study ID
- NCT06805851
- Status
- Recruiting
Conditions
- Depression
- Selective Serotonin Reuptake Inhibitor
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 40 Years
- Healthy Volunteers
- Accepted
Study Details
The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat stress in adults with clinically diagnosed depression, those with depression who are prescribed and taking SSRIs and those with depression who are prescribed and taking SNRIs.
Key Dates
- Start date
- Mar 1, 2025
- Status verified
- Jan 2026
- Primary completion
- Dec 1, 2025
- Completion
- Jan 30, 2027
Study Design
- Enrollment
- 64 participants (estimated)
Arms
- Arm: Non-depressed
- Arm: Depressedadults with clinically diagnosed major depressive disorder
- Arm: SSRIadults with clinically diagnosed major depressive disorder currently taking a physician prescribed selective serotonin reuptake inhibitor as treatment.
- Arm: SNRIadults with clinically diagnosed major depressive disorder currently taking a physician prescribed serotonin norepinephrine reuptake inhibitor as treatment.
Primary Outcome Measure
Skin blood flow [ Time Frame: Monitored continuously during the passive heating experimental trial, about 2 hours. ]
Central Contacts
- W. Larry Kenney814-863-1672
- Kat G Fisher3072037657
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Noll Laboratory | University Park | Pennsylvania | 16802 |
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