Impact of Depression on Thermoregulation

Part of paid clinical trials in University Park, Pennsylvania.

Sponsor
Penn State University
Study ID
NCT06805851
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 40 Years
Healthy Volunteers
Accepted

Study Details

The purpose of this study is to determine if, compared to non-depressed adults, differences exist in skin blood flow and sweating responses to passive heat stress in adults with clinically diagnosed depression, those with depression who are prescribed and taking SSRIs and those with depression who are prescribed and taking SNRIs.

Key Dates

Start date
Mar 1, 2025
Status verified
Jan 2026
Primary completion
Dec 1, 2025
Completion
Jan 30, 2027

Study Design

Enrollment
64 participants (estimated)

Arms

  • Arm: Non-depressed
  • Arm: Depressed
    adults with clinically diagnosed major depressive disorder
  • Arm: SSRI
    adults with clinically diagnosed major depressive disorder currently taking a physician prescribed selective serotonin reuptake inhibitor as treatment.
  • Arm: SNRI
    adults with clinically diagnosed major depressive disorder currently taking a physician prescribed serotonin norepinephrine reuptake inhibitor as treatment.

Primary Outcome Measure

Skin blood flow [ Time Frame: Monitored continuously during the passive heating experimental trial, about 2 hours. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Noll LaboratoryUniversity ParkPennsylvania16802
Kat Fisher
3072037657

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