Type 1 Diabetes Autonomic and Vascular Function

Part of paid clinical trials in Austin, Texas.

Sponsor
University of Texas at Austin
Study ID
NCT06786546
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 70 Years
Healthy Volunteers
Accepted

Study Details

The goal of this clinical trial is to investigate the autonomic and vascular function in men and women with Type 1 diabetes. The main questions it aims to answer are: 1. Patients with type 1 diabetes exhibit attenuated vascular function during steady-state exercise 2. Patients with type 1 diabetes have altered autonomic function at rest and during exercise pressor reflex 3. Patients with type 1 diabetes have attenuated muscle sympathetic activity

Key Dates

Start date
Aug 7, 2023
Status verified
Sep 2025
Primary completion
Dec 31, 2028
Completion
Dec 31, 2029

Study Design

Enrollment
72 participants (estimated)

Arms

  • Arm: Type 1 Diabetes Group
    Men and women diagnosed with Type 1 diabetes
  • Arm: Healthy Control group
    Healthy men and women will be recruited, matched to the Type 1 diabetes group for age, sex and weight

Primary Outcome Measure

Vascular Function [ Time Frame: Blood flow will be measured at baseline for 5 min in supine position. During exercise, blood flow will be measured continuously for the 3 minutes of handgrip exercise. ]

Locations (1)

FacilityCityStateZIPSite coordinators
University of Texas at AustinAustinTexas78712-

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