Exhaled Breath: A Novel Technique for Rapid Diagnosis of Respiratory Diseases and Infections

Part of paid clinical trials in Portland, Oregon.

Sponsor
Oregon Health and Science University
Study ID
NCT06775106
Status
Recruiting
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Conditions

  • Critical Illness
  • Pulmonary Disease

Eligibility Criteria

Sex
ALL
Age
18 Years - 120 Years
Healthy Volunteers
Not accepted

Interventions

  • There is no intervention in this observational study — OTHER
    No direct intervention will be done to patients eligible for the study. There will be a shunt placed to divert 5-15% of exhaled breath into a collection tube. This will not affect the patient's existing standard medical care.

Study Details

This study aims to use mass spectrometry techniques to analyze exhaled patient breath in non-COVID ICU-admitted patients requiring ventilation for a rapid and accurate early detection of pulmonary diseases and inflammatory markers.

Key Dates

Start date
Nov 30, 2024
Status verified
Jan 2025
Primary completion
Dec 31, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
100 participants (estimated)

Arms

  • Arm: non-COVID patients on ventilator support
    There is only one arm in the study, no randomization. Any non-COVID patient admitted to the ICU and requiring ventilation support will be eligible for enrollment into the study.

Primary Outcome Measure

Exhaled breath-based diagnostic platform for detecting ventilator-associated pneumonia (VAP) early in critically ill, mechanically ventilated patients. [ Time Frame: Admission to discharge (up to 30 days) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Oregon Health and Science UniversityPortlandOregon97239
Laura Nguyen, BS
[email protected]
503-418-4733
Albert Chi, MD (PRINCIPAL_INVESTIGATOR)

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