A Study of a Weight Loss Intervention in People With Endometrial Cancer

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT06751589
Phase
EARLY_PHASE1
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tirzepatide — DRUG
    2.5 mg administered using a pre-filled injector once weekly for 4 weeks and then increase to 5 mg once weekly.

Study Details

The researchers are doing this study is to find out whether tirzepatide and semaglutide are practical (feasible) for weight management and blood sugar control for endometrial cancer patients undergoing chemotherapy. The researchers will also look at participants' experience with the study drug, the safety of taking the study drug while receiving chemotherapy, and changes in weight, body fat composition, and blood pressure of participants.

Key Dates

Start date
Dec 19, 2024
Status verified
Apr 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
36 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT

Arms

  • Experimental: tirzepatide
    Patients will meet with the study endocrinologist during screening and be prescribed SC tirzepatide 2.5 mg administered using a pre-filled injector once weekly for 4 weeks and then increase to 5 mg once weekly. If insurance does not cover tirzepatide, the GLP-1 agonist semaglutide (Wegovy, Ozempic) initiated at 0.25 mg weekly SC may be substituted if deemed appropriate by the study PI.

Primary Outcome Measure

percentage of patients that complete treatment [ Time Frame: 1 year ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering Basking RidgeBasking RidgeNew Jersey07920
Sminu Bose, MD
646-888-5427
Memorial Sloan Kettering MonmouthMiddletownNew Jersey07748
Sminu Bose, MD
646-888-5427
Memorial Sloan Kettering BergenMontvaleNew Jersey07645
Sminu Bose, MD
646-888-5427
Memorial Sloan Kettering CommackCommackNew York11725
Sminu Bose, MD
646-888-5427
Memorial Sloan Kettering WestchesterHarrisonNew York10604
Sminu Bose, MD
646-888-5427
Memorial Sloan Kettering Cancer CenterNew YorkNew York10065
Sminu Bose, MD
646-888-5427
Memorial Sloan Kettering NassauUniondaleNew York11553
Sminu Bose, MD
646-888-5427

Find similar trials in Basking Ridge, NJ

By condition
Endometrial cancer
By specialty
OncologyGynecologic oncologyWomen's health
By research site
Memorial Sloan Kettering Basking Ridge· Basking Ridge, NJMemorial Sloan Kettering Monmouth· Middletown, NJMemorial Sloan Kettering Bergen· Montvale, NJMemorial Sloan Kettering Commack· Commack, NYMemorial Sloan Kettering Westchester· Harrison, NYMemorial Sloan Kettering Cancer Center· New York, NY

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