DAANCE FOR CHEMOTHERAPY-INDUCED NEUROPATHY

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Ohio State University Comprehensive Cancer Center
Study ID
NCT06749210
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Cancer of the Breast
  • Chemotherapy-induced Neuropathy

Eligibility Criteria

Sex
ALL
Age
40 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tango — BEHAVIORAL
    The intervention being studied is a 16 session intervention (2x4-week modules), delivered over an 8-week period by community-based individuals with expertise in dance and patient care and certified in Adapted Tango or AdapTango dance instruction. Steps available to teach, including order and cues to teach them, are detailed in Hackney's AdapTango manual. All steps are based on the Argentine Tango steps that emerged within working class community centers in Buenos Aires, Argentina (milongas) in the late 1800s and have been adapted by the investigators for use as medical exercise among people with mobility deficits. Of note, Argentine Tango is distinct from, and the precursor for, the American Tango style of competitive ballroom dance: where American Tango highlights showmanship and complicated footwork, Argentine Tango prioritizes connection between partners and musicality within a basic walk motion.

Study Details

Up to 80% of breast cancer survivors experience chemotherapy-induced neuropathy that impairs quality of life and increases fall risk long into survivorship, yet treatment options for neuropathy remain limited. The successful treatment will target neurophysiologic mechanisms for restoring function while addressing patient-reported symptoms and participation in treatment. Toward this end, the investigators propose to study a noninvasive, social sensorimotor intervention - Adapted Argentine Tango - which targets motor control restoration, symptom alleviation, and treatment participation in concert.

Key Dates

Start date
Feb 19, 2025
Status verified
Jul 2025
Primary completion
Aug 15, 2029
Completion
Aug 15, 2029

Study Design

Enrollment
140 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE

Arms

  • No Intervention: Control
    4 weeks of usual care followed by optional 1-way crossover to 8 weeks of Intervention (partnered, adapted tango dance)
  • Experimental: Experimental
    8 weeks of intervention (partnered, adapted tango dance)

Primary Outcome Measure

Patient-Reported Outcome (PRO) - CIN sensation [ Time Frame: 4 weeks ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Yale UniversityNew HavenConnecticut06520
Maryam Lustberg, MD, MPH
[email protected]
Maryam Lustberg, MD, MPH (PRINCIPAL_INVESTIGATOR)
The Ohio State UniversityColumbusOhio43220
Lise Worthen-Chaudhari, PhD, MFA, CMES
[email protected]
(1) + 614-293-6281
Lise Worthen-Chaudhari, PhD, MFA, CMES (PRINCIPAL_INVESTIGATOR)

Find similar trials in New Haven, CT

By research site
Yale University· New Haven, CTThe Ohio State University· Columbus, OH

Related Studies