Lipoprotein Interactions and Platelet Function in Healthy Individuals and Those With Lipid Disorders
Part of paid clinical trials in East Providence, Rhode Island.
- Sponsor
- The Miriam Hospital
- Study ID
- NCT06747000
- Status
- Recruiting
Conditions
- Lipid Disorders
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 69 Years
- Healthy Volunteers
- Accepted
Study Details
This study looks at how lipoproteins, which are particles in the blood that transport cholesterol, influence heart and blood vessel health. Beyond just their levels, the way these particles function plays a key role in preventing or contributing to disease. In some conditions, like high cholesterol or diabetes, lipoproteins may not work properly, increasing the risk of clogged arteries and other complications. The investigators aim to study these changes in people with lipid disorders to better understand their impact on blood health and to find new ways to prevent and treat heart disease.
Key Dates
- Start date
- Jul 18, 2024
- Status verified
- Sep 2025
- Primary completion
- Jul 18, 2028
- Completion
- Jul 18, 2029
Study Design
- Enrollment
- 80 participants (estimated)
Arms
- Arm: Individuals with lipid disordersIndividuals with lipid disorders (elevated HDL and LDL)
- Arm: Healthy individualsHealthy individuals with normal lipid values and without lipid-related diseases
Primary Outcome Measure
Percentage of platelet aggregation [ Time Frame: 5 years ]
Central Contacts
- Wenliang Song, MD4014449851
- Daria Salamevich7343588165
Locations (2)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Brown University Health Lipid Clinic | East Providence | Rhode Island | 02914 | Wenliang, MD (PRINCIPAL_INVESTIGATOR) |
| Cardiovascular Research Center | Providence | Rhode Island | 02903 | Wenliang Song, MD (PRINCIPAL_INVESTIGATOR) |