Cannabis Effects on Sleep, Circadian Rhythms, and Light Sensitivity in Young Adults

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
University of Pittsburgh
Study ID
NCT06743373
Status
Recruiting
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Conditions

  • Cannabis Use
  • Circadian Rhythm
  • Sleep

Eligibility Criteria

Sex
ALL
Age
18 Years - 25 Years
Healthy Volunteers
Accepted

Interventions

  • Cannabis Discontinuation — BEHAVIORAL
    Cannabis-using participants will participate in an orientation session with a clinician and asked to abstain from cannabis use for four weeks, using established procedures for abstinence monitoring and reinforcement.

Study Details

The goal of this study is to learn how cannabis use and discontinuation affect sleep, circadian rhythms, and sensitivity to light. The main questions it aims to answer are: 1. Does cannabis use and discontinuation impact sleep drive? 2. Does cannabis use and discontinuation impact light sensitivity and circadian phase?

Key Dates

Start date
Mar 13, 2025
Status verified
Apr 2026
Primary completion
Jan 31, 2029
Completion
Apr 30, 2029

Study Design

Enrollment
180 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Cannabis-Using
    The cannabis-using arm will consist of 60 young people reporting regular cannabis use. Participants will complete a 1-week baseline protocol followed by a 4-week cannabis discontinuation protocol (intervention).
  • No Intervention: Control
    The control arm will consist of 30 young people without current cannabis use. Participants will complete a 1-week baseline protocol. No intervention will be administered.

Primary Outcome Measure

Homeostatic Sleep Drive [ Time Frame: Baseline, 1 week ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Western Psychiatric Hospital (Thomas Detre Hall)PittsburghPennsylvania15213
Brant P Hasler, PhD
[email protected]
412-246-6413

Find similar trials in Pittsburgh, PA

By research site
Western Psychiatric Hospital (Thomas Detre Hall)· Pittsburgh, PA

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