Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery

Conditions

• Vocal Cord Cyst
• Vocal Cord Disease
• Vocal Cord Polyp

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Superior laryngeal nerve block - Intervention (Bupivacaine and triamcinolone acetonide suspension) — DRUG
  Patients will receive a superior laryngeal nerve block consisting of 1 ml of 0.25% bupivacaine and 1mL of triamcinolone acetate 40 mg/ml to the neck on the side of the vocal cord lesion during their surgery.
• Superior laryngeal nerve block - Placebo (saline) — DRUG
  Patients will receive a saline placebo of 2mL saline to the neck on the side of the vocal cord lesion during their surgery.

Study Details

Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery. Symptoms such as how much coughing or pain patients have after surgery, as well as whether patient's voice gets better will be interrogated.

Key Dates

Start date

Jul 11, 2025

Status verified

Jan 2026

Primary completion

Dec 31, 2026

Completion

Dec 31, 2026

Study Design

Enrollment

28 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Experimental: Superior laryngeal nerve block
  Patients will receive a superior laryngeal nerve block consisting of 1 milliliter of 0.25% bupivacaine and milliliter of triamcinolone acetate 40 mg/ml to the neck on the side of the vocal cord lesion during their surgery.
• Placebo Comparator: Placebo
  Patients will receive a placebo of 2 milliliter saline injection to the neck on the side of the vocal cord lesion during their surgery.

Primary Outcome Measure

Postoperative pain [ Time Frame: 1, 3 and 7 days after surgery ]

Central Contacts

• Emma Thompson, MD
  973-972-2548
  [email protected]

Locations (1)

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