Femoral BMD Change Following Cemented or Cementless Total Knee Arthroplasty

Part of paid clinical trials in Madison, Wisconsin.

Sponsor
University of Wisconsin, Madison
Study ID
NCT06733597
Status
Recruiting
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Conditions

  • Knee Arthropathy

Eligibility Criteria

Sex
ALL
Age
55 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Cement — PROCEDURE
    The cemented approach includes inserting cement into the femur and tibia prior to setting the prosthetic.
  • Cementless — OTHER
    The non-cement approach uses a different type of prosthetic that is placed tight against the bone and requires no other fixation material.
  • Manual Surgery — PROCEDURE
    The manual approach is the surgeon determining prosthetic placement using techniques developed during training.
  • Robotic Surgery — PROCEDURE
    The haptic robotic assisted approach uses a computer and robot to determine specific placement of the prosthetic.

Study Details

The purpose of this study is to examine femur bone mineral density (BMD) change before and after surgery in patients receiving cemented or cementless total knee arthroplasty (TKA). performed with manual or robotic methods. 100 participants will be enrolled and can expect to be on study for up to 26 months.

Key Dates

Start date
Mar 6, 2025
Status verified
Feb 2026
Primary completion
Jun 30, 2028
Completion
Jun 30, 2028

Study Design

Enrollment
100 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Active Comparator: Cemented and Manual
  • Active Comparator: Cemented and Robotic
  • Active Comparator: Cementless and Manual
  • Active Comparator: Cementless and Robotic

Primary Outcome Measure

Percent Change in Bone Mineral Density within 25 percent of the region of interest at 12 and 24 months post TKA: All Participants [ Time Frame: 12 months, 24 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
UW School of Medicine and Public HealthMadisonWisconsin53792-

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UW School of Medicine and Public Health· Madison, WI

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