Cardiovascular Responses in Burn Survivors During Exercise

Part of paid clinical trials in Dallas, Texas.

Sponsor
University of Texas Southwestern Medical Center
Study ID
NCT06709781
Status
Recruiting
Apply to this trial

Conditions

  • Burn Injury

Eligibility Criteria

Sex
ALL
Age
18 Years - 65 Years
Healthy Volunteers
Accepted

Interventions

  • Control (no cooling modalities) — OTHER
    Subjects will exercise for 60 minutes in the heat while being exposed to no cooling modality.
  • Water Spray — OTHER
    Subjects will exercise for 60 minutes in the heat while being exposed to skin wetting. Skin wetting will be performed by spraying water onto the skin throughout the exercise bout.

Study Details

This project will identify the efficacy of cooling modalities aimed to attenuate excessive elevations in skin and internal body temperatures, and associated indices of cardiovascular stress, during physical activity in well-healed burn survivors. The investigators will conduct a randomized crossover design study. Non-burned control subjects and subjects who experienced burns covering 20% or more of their body surface area will be investigated. Subjects will exercise in heated environmental conditions while receiving no cooling (control) as well as skin wetting.

Key Dates

Start date
Jan 8, 2025
Status verified
Jul 2025
Primary completion
Jan 1, 2027
Completion
Jan 1, 2027

Study Design

Enrollment
36 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER

Arms

  • Experimental: Non-Burned Individuals
    Non-burned individuals will exercise for 60 minutes in the heat while being exposed to either no cooling or cooling via skin wetting (two trials).
  • Experimental: Burn Survivors (20% or more Burn Surface Area burn-injured)
    Burn survivors with 20% or more BSA (burn surface area) burn-injured will exercise for 60 in the heat while being exposed to either no cooling or cooling via skin wetting (two trials).

Primary Outcome Measure

Change in Core Temperature (°C) During Control Intervention [ Time Frame: At 0 minutes and 60 minutes into the intervention. ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Institute for Exercise and Environmental Medicine - Texas Health Presbyterian Hospital DallasDallasTexas75231
Erin M Harper, B.S.
[email protected]
214-345-4737
Craig G Crandall, PhD
[email protected]
214-345-4623

Find similar trials in Dallas, TX

By research site
Institute for Exercise and Environmental Medicine - Texas Health Presbyterian Hospital Dallas· Dallas, TX

Related Studies