Gonadal Tissue Cryopreservation for Fertility Preservation in Children with a Disorder of Sex Development

Part of paid clinical trials in Chicago, Illinois.

Sponsor
Erin Rowell
Study ID
NCT06692049
Status
Recruiting
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Conditions

  • DSD, 46,XY
  • DSD, Ovotesticular
  • DSD, Sex Chromosome
  • Disorder of Sex Development, 46,XY
  • Disorder of Sex Development, 46,Xy, Cbx2-Related
  • Disorders of Sex Development

Eligibility Criteria

Sex
ALL
Age
N/A - 30 Years
Healthy Volunteers
Accepted

Interventions

  • Gonadectomy — PROCEDURE
    Gonadal tissue being removed for risk of malignancy may be cryopreserved for fertility preservation

Study Details

The purpose of this study is to offer gonadal tissue freezing and storage to children who are diagnosed with a disorder of sex development (DSD), who are at increased risk of infertility and certain malignancies (cancer). This study involves the storage of gonadal tissue that is being removed for medical reasons (e.g. prevention of cancer development). It includes the processing and freezing of this gonadal tissue, hopefully for potential future use. The tissue will then be stored long-term until the child wishes to try to use the tissue.

Key Dates

Start date
Apr 4, 2018
Status verified
Nov 2024
Primary completion
Dec 31, 2030
Completion
Dec 31, 2035

Study Design

Enrollment
250 participants (estimated)

Arms

  • Arm: Disorders of Sex Development (DSD)
    The study seeks to find out if removing gonadal tissue in adolescents and children at risk for losing fertility potential (the ability to have children) and who are scheduled to receive a gonadectomy (removal of gonads) for clinical purposes may preserve, or keep, their ability to have children in the future. Additionally, donated research tissue would be used to study long-term ways to preserve and restore reproductive function of children diagnosed with DSD

Primary Outcome Measure

Gonadal Tissue Cryopreservation for Fertility Preservation in Children with Disorders of Sex Development [ Time Frame: 3 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Ann & Robert H. Lurie Children's Hospital of ChicagoChicagoIllinois60611
Sara Reyes
[email protected]
312-227-4145
Erin Rowell, MD

Find similar trials in Chicago, IL

By research site
Ann & Robert H. Lurie Children's Hospital of Chicago· Chicago, IL

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