Predict Tooth Wear
Part of paid clinical trials in Indianapolis, Indiana.
- Sponsor
- Hospices Civils de Lyon
- Study ID
- NCT06681844
- Status
- Recruiting
Conditions
- Prediction of Tooth Wear
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 80 Years
- Healthy Volunteers
- Not accepted
Interventions
- Tooth Shape assessed using an intraoral scanner one after avulsion — OTHER* Tooth Shape assessed using an intraoral scanner one after avulsion and stored as StereoLithography (STL) file * Age, gender, reason of avulsion, type of tooth taken from the database and stored in a google sheet
Study Details
Tooth wear, resulting from gradual loss of dental hard tissue due to mechanical and chemical factors, impacts tooth structure, texture, and function. It affects quality of life, with varying prevalence (26.9% to 90.0%), and is traditionally detected visually during check-ups, often at advanced stages. Monitoring alterations in tooth shape via intraoral scanners aids early detection, but restoration remains challenging. Prevention through early detection is vital, as patients may not fully comprehend tooth structure loss until visible. Recently, statistical shape analysis (SSA) used to learn the tooth anatomy and define a reference shape (biogeneric tooth) using. However, assuring landmark consistency is challenging mostly due to biases of the operator. Recently, a robust method called MEG-IsoQuad offered automated, isotopological remeshing. Combining this with SSA holds promise for diagnostic and simulation purposes. This study aims to assess the reliability of a remeshing-SSA approach for altered and intact premolar analysis and compare machine learning algorithms for simulating the shape of the initially intact tooth or future altered one. The clinical perspective of the current work offers possibilities to: * Prevent future tooth wear by detecting it at an early stage; and communicate better to the patient by presenting him/her potential future altered teeth * Simulate the adapted reconstruction for the altered tooth by simulating the initially intact one
Key Dates
- Start date
- Dec 12, 2023
- Status verified
- Nov 2024
- Primary completion
- Dec 12, 2025
- Completion
- Dec 31, 2027
Study Design
- Enrollment
- 1,000 participants (estimated)
Arms
- Arm: all mature teeth presenting a tooth wear intact or presenting a tooth wear alteredScaling of the tooth before scanning by the operator Evaluation of the tooh wear index 0 or 1 (by 2 calibrated experts )
Primary Outcome Measure
Prediction of the tooth wear index based on a dataset of dental shapes:a retrospective study [ Time Frame: only once ]
Central Contacts
- Raphael Richet, Clinical Assistant+33669523314
- Maxime Ducret, Professor
Locations (1)
| Facility | City | State | ZIP | Site coordinators |
|---|---|---|---|---|
| Indiana University Hospital | Indianapolis | Indiana | 46202 | Anderson Hara |