A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56

Part of paid clinical trials in Phoenix, Arizona.

Sponsor
EyePoint Pharmaceuticals, Inc.
Study ID
NCT06668064
Phase
PHASE3
Status
Active Not Recruiting

Conditions

  • Wet Age Related Macular Degeneration
  • wAMD

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

Study Details

This is a phase 3 randomized, double -masked study comparing the efficacy of EYP-1901 against Aflibercept.

Key Dates

Start date
Oct 22, 2024
Status verified
May 2026
Primary completion
Aug 31, 2026
Completion
Aug 31, 2027

Study Design

Enrollment
400 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: EYP-1901 2686 µg
    EYP-1901
  • Active Comparator: Aflibercept

Primary Outcome Measure

Average change in best corrected visual acuity (BCVA) [ Time Frame: Weeks 52 and 56 ]

Locations (76)

FacilityCityStateZIPSite coordinators
Retinal Research Institute, LLCPhoenixArizona85053-
Retina Partners of Northwest ArkansasSpringdaleArkansas72764-
California Retina ConsultantsBakersfieldCalifornia93309-
Retina Vitreous Associates Medical GroupBeverly HillsCalifornia90211-
Macula and Retina InstituteGlendaleCalifornia91203-
Retina Consultants San DiegoPowayCalifornia92064-
Retina Consultants of Southern CaliforniaRedlandsCalifornia92374-
Retinal Consultants Medical GroupSacramentoCalifornia95841-
Bay Area Retina AssociatesWalnut CreekCalifornia94598-
American Institute of ResearchWhittierCalifornia95008-
RSC Research, PLLCDenverColorado80210-
Eye Center of Northern Colorado, PCFort CollinsColorado80528-
Advanced Vision InstituteLongmontColorado80503-
Connecticut Eye Consultants, P.C.DanburyConnecticut06810-
SightSera Clinical Research LLCGreenwichConnecticut06830-
Retina Group of New England, PCWaterfordConnecticut06385-
Advanced Research, LLCDeerfield BeachFlorida33064-
Florida Retina ConsultantsLakelandFlorida33805-
Florida Retina InstituteOrlandoFlorida32806-
Retina Specialty InstitutePensacolaFlorida32503-
Eye Associates of PinellasPinellas ParkFlorida33782-
MedEye AssociatesSouth MiamiFlorida33143-
Retina Specialists of TampaTampaFlorida33544-
Retina Vitreous Associates of FloridaTampaFlorida33617-
Center for Retina & Macular DiseaseWinter HavenFlorida33880-
Gerogia RetinaMariettaGeorgia30060-
Retina Consultants of Hawaii‘AieaHawaii96701-
Retina AssociatesElmhurstIllinois60126-
University Retina and Macula AssociatesLemontIllinois60439-
Midwest Eye InstituteCarmelIndiana46290-
Retina Associates LLCLenexaKansas66215-
Maine Eye CenterPortlandMaine04101-
The Retina Care CenterBaltimoreMaryland21209-
Retina Groups of WashingtonChevy ChaseMaryland20815-
Cumberland Valley Retina ConsultantsHagerstownMaryland21740-
Retina SpecialistsTowsonMaryland21204-
Ophthalmic Consultants of Boston OCB - BostonBostonMassachusetts02114-
New England Retina ConsultantsSpringfieldMassachusetts01107-
Retina Associates of MichiganGrand BlancMichigan48439-
Foundation for Vision ResearchGrand RapidsMichigan49546-
Deep Blue Retina Clinical Research PLLCSouthavenMississippi38671-
The Retina InstituteSt LouisMissouri63128-
Sierra Eye AssociatesRenoNevada89502-
NJ RetinaTeaneckNew Jersey07666-
NJ RetinaToms RiverNew Jersey08755-
Vision Research Center at Eye Associates of New MexicoAlbuquerqueNew Mexico87109-
Retina Vitreous Surgeons of CNY, PCLiverpoolNew York13088-
Retina Associates of Western NY, PCRochesterNew York14620-
Retina Consultants PLLCSlingerlandsNew York12159-
Western Carolina Retinal Associates, PAAshevilleNorth Carolina28803-
Cape Fear Retinal Associates, PCWilmingtonNorth Carolina28401-
Piedmont Retina Specialists, P.A. - Winston-Salem OfficeWinston-SalemNorth Carolina27103-
Tulsa Retina ConsultantTulsaOklahoma74114-
Verum Research LLCEugeneOregon97401-
Erie Retina ResearchEriePennsylvania16507-
Eye Care Specialists - Kingston LocationKingstonPennsylvania18704-
Retina ConsultantsCharlestonSouth Carolina29414-
Palmetto Retina CenterFlorenceSouth Carolina29169-
Retina Consultants of Carolina P.AGreenvilleSouth Carolina29605-
Charles Retina InstituteGermantownTennessee38138-
Retina Research Institute of Texas Integrated Clinical ResearchAbileneTexas79606-
Retina and Vitreous of TexasBellaireTexas77401-
Retina Consultants of Texas (Retina Consultants of Houston) - WoodlandsBellaireTexas77401-
Texas Retina AssociatesDallasTexas75231-
Texas Retina AssociatesPlanoTexas75075-
Retinal Consultants of TexasSan AntonioTexas78240-
San Antonio Eye CenterSan AntonioTexas78215-
Retina Consultants of TexasThe WoodlandsTexas77384-
Tyler Retina ConsultantsTylerTexas75703-
Strategic Clinical Research Group, LLCWillow ParkTexas76087-
Retina Associates of UtahSalt Lake CityUtah84107-
Salt Lake RetinaWest JordanUtah84088-
The Retina Group of WashingtonFairfaxVirginia22031-
Piedmont Eye CenterLynchburgVirginia24502-
Retina Associates, P.C.WinchesterVirginia22601-
University of Wisconsin School of Medicine and Public Health (UWSMPH)MadisonWisconsin53705-

Find similar trials in Phoenix, AZ

By research site
Retinal Research Institute, LLC· Phoenix, AZRetina Partners of Northwest Arkansas· Springdale, ARCalifornia Retina Consultants· Bakersfield, CARetina Vitreous Associates Medical Group· Beverly Hills, CAMacula and Retina Institute· Glendale, CARetina Consultants San Diego· Poway, CA

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