Does Ethyl Chloride Spray Work?

Conditions

• Injection Complication
• Injection Fear
• Injection Pain Prevention

Eligibility Criteria

Sex

ALL

Age

18 Years - N/A

Healthy Volunteers

Not accepted

Interventions

• Ethyl Chloride — OTHER
  Topical anesthetic that rapidly cools the skin and underlying tissues
• Cold Saline Spray — OTHER
  placebo application of cold saline spray

Study Details

A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal tunnel syndrome, trigger finger, and de Quervain's tenosynovitis. While these injections have demonstrated effectiveness in alleviating symptoms, the discomfort associated with the procedure can be a source of anxiety and apprehension for patients. This discomfort arises from the sensation of the needle entering the affected area and the burning sensation induced by the corticosteroid solution.

Key Dates

Start date

Apr 1, 2025

Status verified

Apr 2025

Primary completion

Dec 31, 2027

Completion

Dec 1, 2028

Study Design

Enrollment

300 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Arms

• Experimental: Freeze spray group
  Ethyl Chloride Usage Prior to Orthopaedic Injections
• Placebo Comparator: Placebo application of cold saline spray
  Saline spray before injection
• No Intervention: No spray prior to injection
  No intervention before injection

Primary Outcome Measure

To determine if freeze spray usage before corticosteroid injections significantly reduces patient discomfort during the procedure as measured by pain scores before injection [ Time Frame: 10 minutes before subject receives injection ]

Central Contacts

• Jennifer M Wolf, MD, PhD
  773-834-3531
  [email protected]
• Jordan Swindle, MD
  [email protected]

Locations (1)

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