Effect of Low Water Intake on Glucose Regulation Measured Using Continuous Glucose Monitoring

Conditions

• Blood Glucose Concentration
• Blood Glucose Self Monitoring

Eligibility Criteria

Sex

ALL

Age

18 Years - 55 Years

Healthy Volunteers

Accepted

Interventions

• Water Intake — BEHAVIORAL
  Previous studies have not observed blood glucose with adequate vs. low water intake in a free-living situation. The use of continuous glucose monitors allows this.

Study Details

This clinical trial aims to learn if increasing water intake for five days can lower blood glucose in healthy, free-living individuals. The main question it aims to answer is whether increasing water intake will reduce daily blood glucose. Researchers will compare blood glucose when drinking adequate water to when the same individuals drink a low amount of water to see if blood glucose differs with water intake. Participants will be asked to drink a prescribed volume of water over two weeks while wearing a continuous glucose monitor and collecting two urine voids throughout each day.

Key Dates

Start date

Oct 1, 2024

Status verified

Oct 2024

Primary completion

Jul 31, 2025

Completion

Aug 31, 2025

Study Design

Enrollment

20 participants (estimated)

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

PREVENTION

Arms

• Experimental: High water intake
  For six days, participants will consume the NAM's recommended total water intake of 2.7 liters per day for women and 3.7 liters per day for men
• Active Comparator: Low water intake
  For six days, participants will consume 0.7 liters per day for women and 1 liter per day for men.

Primary Outcome Measure

Daily blood glucose [ Time Frame: 14 days ]

Locations (1)

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