Circadian Mechanisms, Glucose, and CV Risks in T1D

Part of paid clinical trials in Chicago, Illinois.

Sponsor
University of Illinois at Chicago
Study ID
NCT06624046
Status
Recruiting
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Conditions

  • Type 1 Diabetes (T1D)

Eligibility Criteria

Sex
ALL
Age
18 Years - 50 Years
Healthy Volunteers
Not accepted

Interventions

  • Sleep stability intervention — BEHAVIORAL
    The sleep stability intervention will consist of three theory-based intervention components our team has developed and used in prior interventions: 1) self-monitoring using a wearable sleep tracker (Fitbit). This is well-liked by participants and increases awareness of their sleep goals. 2) Accountability coaching via weekly check-ins and daily monitoring of participants' wearable sleep tracking data and a coaching protocol.

Study Details

People with type 1 diabetes are disproportionately affected by cardiovascular disease (CVD). Short and irregular sleep have been associated with cardiovascular risk in this population. Improving sleep regularity has been associated with improved glycemic markers however mechanisms by which improving sleep regularity improves metabolic and cardiovascular health is not known. The investigators propose to conduct a mechanistic study using a sleep stability manipulation. This proposal will advance the understanding of mechanisms by which improving sleep regularity influences glycemic control and cardiovascular risk in T1D.

Key Dates

Start date
Mar 13, 2025
Status verified
Aug 2025
Primary completion
Feb 28, 2029
Completion
Aug 31, 2029

Study Design

Enrollment
100 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Other: Single arm
    Sleep stability intervention

Primary Outcome Measure

Glycemic status [ Time Frame: From enrollment to week 12 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Illinois ChicagoChicagoIllinois60612
Pamela Martyn-Nemeth, PhD
[email protected]
312-996-7903
Sirimon Reutrakul, MD
[email protected]
312-413-3631
Pamela Martyn-Nemeth, PhD (PRINCIPAL_INVESTIGATOR)
Sirimon Reutrakul, MD (PRINCIPAL_INVESTIGATOR)

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