Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients

Part of paid clinical trials in Los Angeles, California.

Sponsor
Charles Drew University of Medicine and Science
Study ID
NCT06615752
Phase
PHASE1/PHASE2
Status
Recruiting
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Conditions

  • Metastatic Castration-resistant Prostate Cancer (mCRPC)

Eligibility Criteria

Sex
MALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • green tea and quercetin + docetaxel — DRUG
    green tea and quercetin supplements in combination with docetaxel infusion
  • Placebo + docetaxel — DRUG
    Placebo will be given along with docetaxel chemotherapy

Study Details

The goal of this clinical trial is to find out if taking natural products green tea and quercetin along with docetaxel chemotherapy improves the therapy of advanced prostate cancer, i.e., metastatic castration-resistant prostate cancer (mCRPC). It will also learn about the safety of this combination. Researchers will compare green tea plus quercetin to a placebo (a look-alike substance that contains no drug) in combination with docetaxel to see if green tea and quercetin works to improve the therapeutic effect of docetaxel.

Key Dates

Start date
Oct 31, 2026
Status verified
Apr 2026
Primary completion
Apr 30, 2028
Completion
Feb 28, 2029

Study Design

Enrollment
99 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: green tea and quercetin
    Green tea and quercetin capsules will be administered in combination with docetaxel treatment.
  • Placebo Comparator: placebo
    Placebo capsules will be administered in combination with docetaxel treatment as comparison.

Primary Outcome Measure

Efficacy evaluated with blood prostate specific antigen (PSA) level [ Time Frame: From enrollment to the end of treatment at 11 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Charles R. Drew University of Medicine and ScienceLos AngelesCalifornia90059
Piwen Wang, PhD
[email protected]
323-563-4999

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By research site
Charles R. Drew University of Medicine and Science· Los Angeles, CA

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