Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training

Part of paid clinical trials in San Antonio, Texas.

Sponsor
The Geneva Foundation
Study ID
NCT06606925
Status
Recruiting

Conditions

  • Cognitive Performance

Eligibility Criteria

Sex
ALL
Age
18 Years - 54 Years
Healthy Volunteers
Not accepted

Interventions

  • fMRI with virtual reality flight simulator — DIAGNOSTIC_TEST
    During this scan, the subject will be wearing the stereogenic goggles called the Visual System HD (NordicNeuroLab) mounted in the scanner via a headcoil that can be adjusted to the subject's comfort using the control arm and completely cover the eyes to prevent light exposure and to clearly visualize eye movement during the flight simulation. The subject will be using a visual response system with customized grips to simulate a stick and throttle in a jet cockpit while visualizing the flight simulation (PICT) in the goggles.

Study Details

The overall objective is to identify the cognitive circuits associated with military aviator performance by analyzing what anatomic regions of the brain are functionally "active" (neuronal circuit) while being performing virtual flight simulations, the Precision Instrument Control Task (PICT). The flight simulation test will be conducted at two separate timepoints while the subject is receiving a Functional Magnetic Resonance Imaging (fMRI) scan to evaluate which anatomic and functional brain function is associated with precise performance. By scanning at multiple time points we aim to quantify changes in functional and anatomic connectivity that occur throughout the course of training.

Key Dates

Start date
Sep 19, 2023
Status verified
Jan 2025
Primary completion
Mar 30, 2026
Completion
Sep 18, 2026

Study Design

Enrollment
150 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: Functional (fMRI) and anatomic MRI imaging a two timepoints during pilot virtual reality simulation
    Initial anatomic imaging and fMRI with virtual reality flight simulator scan with repeat testing performed at approximately 2 months (+/- 1 month) after initial scan.

Primary Outcome Measure

Flight simulation scores of responses (reaction times and latency) [ Time Frame: From enrollment to the end of treatment at 30 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Joint Base San Antonio - Randolph & LacklandSan AntonioTexas78150
Ayla Ulfberht, Research Coordinator, BS
Bianca Cequeira, Associate Investigator, PhD
(210) 292-4604
Bianca Cequeira, PhD (SUB_INVESTIGATOR)

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