Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 2

Part of paid clinical trials in Madison, Wisconsin.

Sponsor
University of Wisconsin, Madison
Study ID
NCT06601699
Status
Recruiting
Apply to this trial

Conditions

  • Healthy

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Accepted

Interventions

  • Transcranial electrical stimulation (TES) — DEVICE
    TES uses specific electrode arrangement patterns to selectively stimulate the brain. Participants will wear an hdEEG (high density electroencephalography) cap which will allow intermittent periods of stimulation from TES.
  • Transcranial electrical stimulation with temporal interference (TES-TI) — DEVICE
    TES-TI uses specific electrode arrangement patterns to selectively stimulate the brain. Participants will wear an hdEEG (high density electroencephalography) cap which will allow intermittent periods of stimulation from TES-TI.

Study Details

The goal of this clinical trial is to learn whether brain stimulation technology can help people reach a meditative state quickly and easily without years of meditation training. The researchers want to see if this will help people distance themselves from their thoughts and feeling, and if this will lead to improvements in openness and wellbeing the same way meditation can. Participants will: * Complete questionnaires * Perform a guided meditation task (The Bell Task) * Wear a high density electrocochleography (hdEEG) cap * Undergo brain stimulation

Key Dates

Start date
Aug 27, 2025
Status verified
Nov 2025
Primary completion
Jul 31, 2027
Completion
Jul 31, 2028

Study Design

Enrollment
48 participants (estimated)
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Stimulation
    Participants will undergo TES or TES-TI stimulation in 5-minute blocks up to eight times a day on three separate days each separated by one week.
  • Sham Comparator: Sham stimulation
    Participants will undergo sham stimulation in 5-minute blocks up to eight times a day on three separate days each separated by one week.

Primary Outcome Measure

Ego-Disengagement scale [ Time Frame: baseline, week 1, week 2, week 3, week 7 ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of WisconsinMadisonWisconsin53719
Simone Bruno
[email protected]
608-209-4108
Melanie Boly, MD, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Wisconsin· Madison, WI

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