Cardiac Radioablation for VT

Part of paid clinical trials in Royal Oak, Michigan.

Sponsor
Corewell Health East
Study ID
NCT06593418
Status
Not Yet Recruiting

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Conditions

  • Myocardial Infarction
  • Ventricular Tachycardia

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Stereotactic Body Radiation Therapy (SBRT) — RADIATION
    Stereotactic body radiation therapy, which delivers precise, high-dose radiation non-invasively to generate thermal scarring to myocardial targets causing VT

Study Details

The goal of this interventional study is to determine the minimum dose necessary for successful cardiac radioablation of refractory ventricular tachycardia (VT) and to study the utility of target volume definition using Delayed Enhancement Cardiac MRI (DE-CMR) .

Key Dates

Start date
Jul 31, 2026
Status verified
Apr 2026
Primary completion
Jan 31, 2028
Completion
Jan 31, 2028

Study Design

Enrollment
24 participants (estimated)
Allocation
NON_RANDOMIZED
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT

Arms

  • Experimental: Radiation Therapy at 15 Gy for Ventricular Tachycardia
    Post myocardial infarction patients with refractory ventricular tachycardia requiring cardio ablation, treated with 15 Gy
  • Experimental: Radiation Therapy at 20 Gy for Ventricular Tachycardia
    Post myocardial infarction patients with refractory ventricular tachycardia requiring cardio ablation, treated with 20 Gy
  • Experimental: Radiation Therapy at 25 Gy for Ventricular Tachycardia
    Post myocardial infarction patients with refractory ventricular tachycardia requiring cardio ablation, treated with 25 Gy

Primary Outcome Measure

Change in number of ventricular tachycardia (VT) episodes from pre-cardiac radioablation to post-cardiac radioablation [ Time Frame: 56 days pre-treatment and 98 days post treatment (42 day blanking period plus 56 days) ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Corewell Health William Beaumont University HospitalRoyal OakMichigan48073
John Robertson, MD
[email protected]
(248) 551-7038

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By research site
Corewell Health William Beaumont University Hospital· Royal Oak, MI

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