The Effects of Patient and Visit Characteristics on Health Outcomes in Knee Osteoarthritis

Part of paid clinical trials in Sacramento, California.

Sponsor
University of California, Davis
Study ID
NCT06574191
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Topical Diclofenac gel 1% — DRUG
    Topical NSAID

Study Details

The goal of this clinical trial is to understand the patient and clinic visit characteristics that affect health outcomes for individuals with knee osteoarthritis (OA) pain using topical diclofenac gel. The main questions it aims to answer are: * What baseline patient characteristics predict response to topical diclofenac? * Does patient physiology during the study visit predict response to topical diclofenac? * Do study visit characteristics predict response to topical diclofenac? Participants will: * attend 2 study visits to complete study questionnaires and have blood drawn * apply topical diclofenac to their knee for 8 weeks * complete biweekly questions about knee pain and diclofenac use between study visits

Key Dates

Start date
Jan 29, 2025
Status verified
Mar 2026
Primary completion
Jan 27, 2028
Completion
Jan 27, 2028

Study Design

Enrollment
220 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Diclofenac
    All study participants receiving topical diclofenac gel 1%. Participants will be instructed to apply 4 grams of the gel to the index knee at least once per day, and up to 4 times per day, for 8 weeks.

Primary Outcome Measure

Knee Pain [ Time Frame: 8 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of California Davis HealthSacramentoCalifornia95817
Michelle Dossett, MD, PhD, MPH
[email protected]
916-734-5367

Find similar trials in Sacramento, CA

By condition
Osteoarthritis (other)
By specialty
OrthopedicsMusculoskeletal disorders
By research site
University of California Davis Health· Sacramento, CA

Related Studies