Selinexor, Anti-PD-1 Antibody Plus Golidocitinib in R/R NKTCL
- Sponsor
- Ruijin Hospital
- Study ID
- NCT06573138
- Phase
- PHASE2
- Status
- Not Yet Recruiting
Notify me when recruiting opens
Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.
Add your contact details and location so we can keep your interest tied to this study.
Conditions
- Lymphoma, Extranodal NK-T-Cell
Eligibility Criteria
- Sex
- ALL
- Age
- 14 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Selinexor, anti-PD-1 antibody plus Golidocitinib — DRUGSelinexor, 40mg, qw, po; anti-PD1 antibody, 200mg, d1, i.v. (21d cycle); Golidocitinib, Dose 1, 150mg, qod, po; Dose2, 150mg, qd, po.
Study Details
A multicenter, prospective trial to evaluate the efficacy and safety of Selinexor, anti-PD-1 antibody plus Golidocitinib in the treatment of relapsed or refractory Natural Killer / T-cell lymphoma.
Key Dates
- Start date
- Sep 1, 2024
- Status verified
- Aug 2024
- Primary completion
- Jul 1, 2027
- Completion
- Jul 1, 2027
Study Design
- Enrollment
- 18 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: ChemofreePatients receive 3 cycles of Selinexor, anti-PD-1 antibody plus Golidocitinib.
Primary Outcome Measure
Best CRR [ Time Frame: through study completion, an average of 1 year ]
Central Contacts
- Weili Zhao, Prof.008602164370045