A Study Comparing Cancer Imaging Approaches in People With Lobular Breast Cancer

Part of paid clinical trials in Basking Ridge, New Jersey.

Sponsor
Memorial Sloan Kettering Cancer Center
Study ID
NCT06557148
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • 18F-Fluoroestradiol PET/CT — DIAGNOSTIC_TEST
    Scanned at baseline and again posttreatment within 2 weeks of the restaging FDG PET/CT

Study Details

The purpose of this study to compare two types of cancer imaging scans to see which is better at detecting and monitoring metastatic ILC. This study will compare PET/CT (positron emission tomography/computed tomography) scans using the radiotracer fluorine 18 (18F)-fluoroestradiol (FES) with a standard imaging approach for detecting and monitoring ILC, PET/CT scans using the radiotracer 18F-fluorodeoxyglucose (FDG). These scans will be referred to as FES PET/CT scans and FDG PET/CT scans.

Key Dates

Start date
Aug 13, 2024
Status verified
Feb 2026
Primary completion
Aug 13, 2027
Completion
Aug 13, 2027

Study Design

Enrollment
30 participants (estimated)

Arms

  • Arm: Biopsy-proven ER+ Metastatic Invasive Lobular Carcinoma/ILC
    Participants will have biopsy-proven metastatic ILC, confirmed ER+ breast cancer

Primary Outcome Measure

Comparison of FES PET/CT in Metastatic Invasive Lobular Carcinoma/ILC to standard-of-care (SOC) imaging with FDG PET/CT at baseline [ Time Frame: 1 year ]

Central Contacts

Locations (7)

FacilityCityStateZIPSite coordinators
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking RidgeNew Jersey07920
Somali Gavane, MD
212-639-2403
Memorial Sloan Kettering Monmouth (Limited protocol activities)MiddletownNew Jersey07748
Somali Gavane, MD
212-639-2403
Memorial Sloan Kettering Bergen (All Protocol Activities)MontvaleNew Jersey07645
Somali Gavane, MD
212-639-2403
Memorial Sloan Kettering Suffolk-Commack (All protocol activity)CommackNew York11725
Somali Gavane, MD
212-639-2403
Memorial Sloan Kettering Westchester (Limited Protocol Activities)HarrisonNew York10604
Somali Gavane, MD
212-639-2403
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New YorkNew York10065
Somali Gavane, MD
212-639-2403
Memorial Sloan Kettering Nassau (Limited Protocol Activites)Rockville CentreNew York11553
Somali Gavane, MD
212-639-2403

Find similar trials in Basking Ridge, NJ

By condition
Breast cancer
By specialty
OncologyBreast oncologyWomen's health
By research site
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)· Basking Ridge, NJMemorial Sloan Kettering Monmouth (Limited protocol activities)· Middletown, NJMemorial Sloan Kettering Bergen (All Protocol Activities)· Montvale, NJMemorial Sloan Kettering Suffolk-Commack (All protocol activity)· Commack, NYMemorial Sloan Kettering Westchester (Limited Protocol Activities)· Harrison, NYMemorial Sloan Kettering Cancer Center (All Protocol Activities)· New York, NY

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