Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

Part of paid clinical trials in Ames, Iowa.

Sponsor
National Human Genome Research Institute (NHGRI)
Study ID
NCT06552754
Status
Recruiting
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Conditions

  • Healthy Volunteers
  • Virtual Reality

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • Motion Reset — BEHAVIORAL
    virtual reality-based experiential, sensory intervention
  • Placebo — BEHAVIORAL
    virtual reality-based experiential, sensory experience without intervention

Study Details

Background: People use virtual reality (VR) technology to play games, socialize, work, or receive medical care. Some people have "cybersickness" after using VR. Cybersickness is similar to motion sickness. Symptoms include eye strain, nausea, dizziness, or headache. The symptoms are usually mild and go away after the person stops using VR. New software called Motion Reset is being designed to reduce symptoms of cybersickness during VR use. Objective: To see if Motion Reset software can reduce cybersickness in people using VR. Eligibility: Healthy adults aged 18 to 60 years. Design: Participants will have 1 clinic visit that will last about 1 hour. They will answer questions about how they are feeling. They will learn how to use the VR headset and the handheld game controllers. The study will be broken into 2 parts. For the first part, participants will be assigned to 1 of 3 groups: Group 1 will participate in a VR experience designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller. Group 2 will participate in a VR experience that is not designed to prevent cybersickness. They will view screens and move around while they press buttons on a controller. Group 3 will have no VR experience. Participants will complete 2 questionnaires about their experiences in the first part of the study. For the second part, all participants will spend up to 20 minutes playing a commercial VR game called Jurassic World Aftermath. Every few minutes, they will be asked if they are experiencing discomfort. After playing the game, participants will complete 12 questionnaires about their experience....

Key Dates

Start date
Sep 26, 2025
Status verified
May 2026
Primary completion
Feb 1, 2027
Completion
Feb 1, 2027

Study Design

Enrollment
150 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: Intervention: Motion Reset
    Participate in virtual reality activities
  • No Intervention: No intervention
  • Placebo Comparator: Placebo experience
    Participate in virtual reality activities

Primary Outcome Measure

self-reported cybersickness [ Time Frame: during and after VR use ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
Iowa State UniversityAmesIowa50011-
National Institutes of Health Clinical CenterBethesdaMaryland20892
NIH Clinical Center Office of Patient Recruitment (OPR)
[email protected]
800-411-1222

Find similar trials in Ames, IA

By research site
Iowa State University· Ames, IANational Institutes of Health Clinical Center· Bethesda, MD

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