A Study of Microwave Ablation Combined With Immunotherapy ± Anti-angiogenic Drugs in the Treatment of Solid Tumors
- Sponsor
- Beidahuang Industry Group General Hospital
- Study ID
- NCT06537505
- Phase
- PHASE2
- Status
- Not Yet Recruiting
Notify me when recruiting opens
Save your spot on the interest list for this study. We'll keep your details with this study so our team can follow up when recruiting opens.
Add your contact details and location so we can keep your interest tied to this study.
Conditions
- Solid Tumor
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 75 Years
- Healthy Volunteers
- Not accepted
Interventions
- Adebrelimab — DRUGQ3W,IV
- Apatinib — DRUGQoD
- microwave ablation — PROCEDUREmicrowave ablation
Study Details
This is a multi-center, phase Il trial to evaluate the efficacy and safety of microwave ablation combined with immunotherapy ± anti-angiogenic drugs in the treatment of advanced second-line and above solid tumors.
Key Dates
- Start date
- Aug 5, 2024
- Status verified
- Aug 2024
- Primary completion
- Apr 1, 2027
- Completion
- Aug 31, 2027
Study Design
- Enrollment
- 60 participants (estimated)
- Allocation
- NON_RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- TREATMENT
Arms
- Experimental: microwave ablation combined with immunotherapy and anti-angiogenic drugsmicrowave ablation combined with adebrelimab and apatinib
- Experimental: microwave ablation combined with immunotherapymicrowave ablation combined with adebrelimab
Primary Outcome Measure
Objective Response Rate [ Time Frame: up to 24 months ]
Central Contacts
- Mingyang Liu+86 451 5519 7857
Related Studies
- A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)PHASE1/PHASE2 · Recruiting · Merck Sharp & Dohme LLC · Aurora, Colorado
- Metronomic Therapy for Pediatric Patients With Solid Tumors at High Risk of RecurrenceEARLY_PHASE1 · Recruiting · Miller Children's & Women's Hospital Long Beach · Long Beach, California
- Umbilical Cord Blood Transplantation From Unrelated DonorsRecruiting · University of Rochester · Rochester, New York
- Dabrafenib and/or Trametinib Rollover StudyPHASE4 · Recruiting · Novartis Pharmaceuticals · Scottsdale, Arizona