Plexaa For Preconditioning: Gender Affirming Mastectomy

Part of paid clinical trials in Palo Alto, California.

Sponsor
Plexaa Ltd
Study ID
NCT06502353
Status
Recruiting

Conditions

  • Nipple Graft Loss
  • Nipple Necrosis

Eligibility Criteria

Sex
FEMALE
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • BLOOM43 — DEVICE
    Heat preconditioning

Study Details

The goal of this clinical trial is to evaluate the use of the Plexaa preconditioning device (BLOOM43) in transgender and non-binary patients undergoing gender affirming mastectomy. This study aims to understand a participant's experience of the device, including its usability and acceptability. Participants will use the device to precondition their right breast the evening before undergoing surgery (gender affirming mastectomy).

Key Dates

Start date
Aug 20, 2025
Status verified
Sep 2025
Primary completion
Jan 1, 2026
Completion
Jun 1, 2026

Study Design

Enrollment
15 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION

Arms

  • Experimental: All participants (single arm)
    Each patient will be given the device, BLOOM43, for use at home. It will be worn in a patient's existing bra over their right breast and the preconditioning protocol will be done 12 hours before surgery - i.e. the evening before. Patients will then attend their breast surgery the next day as planned.

Primary Outcome Measure

Participant experience [ Time Frame: 30 days ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Division of Plastic & Reconstructive Surgery, Stanford UniversityPalo AltoCalifornia94304
Dung Nguyen
650-498-6004

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