Improving Vaccine Acceptance Through EHR Integrated Patient- and Provider-Facing Decision Support

Part of paid clinical trials in Atlanta, Georgia.

Sponsor
Johns Hopkins Bloomberg School of Public Health
Study ID
NCT06482450
Status
Recruiting
Apply to this trial

Conditions

  • Vaccine Hesitancy
  • Vaccine Refusal

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Accepted

Interventions

  • LetsTalkShots (patient-facing CDS) — OTHER
    LetsTalkShots is a website which provides patients/parents with tailored videos addressing vaccine concerns.
  • LetsTalkShots (provider-facing CDS) — OTHER
    The provider-facing CDS component will propagate patient concerns obtained from LetsTalkShots (and the appropriate talking points to address the talking points) into the electronic health record (EHR) for the provider at the point of care.
  • Appointment Reminder Message — OTHER
    The regular text message and e-mail appointment reminder includes a vaccine primer (e.g. "Vaccines are due and reserved for the participant's child"), but no patient- or provider-facing CDS.

Study Details

The goal of this project is to establish the technical feasibility of a scalable, integrated platform to improve patient informed decision-making and increase vaccine uptake and to evaluate the effectiveness of the integrated platform to improve vaccine uptake.

Key Dates

Start date
Jun 11, 2025
Status verified
May 2026
Primary completion
May 11, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
1,200 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Patient- and Provider-Facing CDS
    Parents of patients with odd birthdates (e.g. April 13) and vaccines due at the index appointment who also have a MYchart account will receive a text message directing the parent to the LTS server with integration into the provider workflow
  • Experimental: Patient-Facing CDS Only
    Among patients without a MYchart account, those with odd birthdates will receive a link to the LTS website (patient-facing CDS) but no integration into the provider workflow.
  • Placebo Comparator: Control (MYchart account)
    Patients with an even birthdate (e.g. April 14) who have a MYchart account will receive a regular text message and e-mail appointment reminder with a vaccine primer (e.g. "Vaccines are due and reserved for the participant's child"), but no patient- or provider-facing CDS.
  • Placebo Comparator: Control (no MYchart account)
    As in the other control group, those without a MYchart account and an even birthdate (e.g. April 14) will receive a text message and e-mail appointment reminder with a vaccine primer but no patient- or provider-facing CDS.

Primary Outcome Measure

Vaccination rate [ Time Frame: Baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Children's Healthcare of Atlanta Hughes Spalding Primary Care ClinicAtlantaGeorgia30303
404-785-9850

Find similar trials in Atlanta, GA

By research site
Children's Healthcare of Atlanta Hughes Spalding Primary Care Clinic· Atlanta, GA

Related Studies