Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech

Part of paid clinical trials in Orlando, Florida.

Sponsor
University of Central Florida
Study ID
NCT06467136
Status
Recruiting
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Conditions

  • Apraxia of Speech
  • Apraxia, Oral

Eligibility Criteria

Sex
ALL
Age
18 Years - 90 Years
Healthy Volunteers
Not accepted

Interventions

  • Sound production treatment — BEHAVIORAL
    Evidence based treatment for apraxia of speech, developed by Julie Wambaugh.
  • Motor Imagery Practice — BEHAVIORAL
    Practice of target items using motor imagery during home practice

Study Details

Treatment of post-stroke apraxia of speech (AOS) requires frequent and ongoing practice with a speech-language pathologist to facilitate lasting behavioral change, which is costly and, therefore, inaccessible to many patients. Thus, there is a critical need to identify novel, cost-effective ways to supplement speech therapy to increase opportunities for practice and optimize treatment outcomes. Our long-term goal is to develop an effective, home-practice, computer-based, motor imagery protocol Motor Imagery for Treatment Enhancement and Efficacy (MI-TEE) which will serve as an adjunct to routine speech therapy to optimize treatment response in persons with AOS. The overall objectives of this application are to (i) evaluate the acceptability and feasibility of MI-TEE as a home practice program and (ii) determine the efficacy of MI-TEE with speech therapy, compared to speech therapy alone, in improving speech production in people with AOS. Our central hypothesis is that MI-TEE will be an accessible, feasible, and efficacious adjunct to speech therapy. To attain our objectives, the following specific aims will be pursued using two single-subject experimental designs with multiple baselines across participants (n=18): 1) Evaluate the acceptability and feasibility of MI-TEE as an adjunct to speech therapy for the rehabilitation of AOS; and 2) Compare the efficacy of adjunctive MI-TEE plus standard speech therapy to standard speech therapy alone. Under the first aim, observational data, surveys, and semi-structured interviews will be employed to assess the acceptability (perceived satisfaction, appropriateness, and intent to continue use) and feasibility (recruitment, retention, and intervention adherence rates) of MI-TEE. For the second aim, accuracy of articulation for trained words and untrained words (generalization) will be measured pre-treatment, repeatedly during the treatment phase, and post-treatment. Improvements in speech accuracy will be documented using a binary scoring system (correct/incorrect). Multilevel analyses will be used to address rate of acquisition, overall change, and response variation across participants.

Key Dates

Start date
Dec 11, 2023
Status verified
Jun 2024
Primary completion
Jul 31, 2026
Completion
Jul 31, 2026

Study Design

Enrollment
18 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Condition 1
    Condition 1 will have three phases: (A) no treatment; (B) speech therapy alone; (C) speech therapy plus MI-TEE (the home practice program).
  • Experimental: Condition 2
    Condition 2 will include two phases: (A) no treatment; (C) speech therapy plus MI-TEE (the home practice program).

Primary Outcome Measure

Acceptability [ Time Frame: Assessment of acceptability will occur after completion of the 8.3 week treatment program ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Central Florida Innovation Rehabilitation CenterOrlandoFlorida32826
Lauren Bislick Wilson, PhD
[email protected]
407-823-4768
Stephanie Eaton, MA
[email protected]
407-823-4768
Lauren Bislick Wilson, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
University of Central Florida Innovation Rehabilitation Center· Orlando, FL

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