Investigation of Filaggrin Gene Mutations Among Latinx Patients With Atopic Dermatitis

Part of paid clinical trials in Philadelphia, Pennsylvania.

Sponsor
University of Pennsylvania
Study ID
NCT06464133
Status
Enrolling By Invitation

Conditions

Eligibility Criteria

Sex
ALL
Age
N/A - N/A
Healthy Volunteers
Not accepted

Study Details

The study, Investigation of Filaggrin Gene Mutations among Latinx patients with Atopic Dermatitis, will examine the association between pathogenic FLG LOF variants and AD in a new population of Latinx patients for which clinical and disease characteristics will be well-described.

Key Dates

Start date
Jan 23, 2025
Status verified
Apr 2026
Primary completion
Dec 31, 2027
Completion
Dec 31, 2027

Study Design

Enrollment
300 participants (estimated)

Primary Outcome Measure

To identify and describe Filaggrin (FLG) loss of function (LOF) variants in the GAD-L cohort using a high-throughput PCR approach that incorporates Fluidigm microfluidics technology and next-generation sequencing (NGS) to sequence the entire FLG gene. [ Time Frame: 2 year data/sample collection period - cross-sectional cohort study of patients with a diagnosis of atopic dermatitis ]

Locations (1)

FacilityCityStateZIPSite coordinators
The University of PennsylvaniaPhiladelphiaPennsylvania19140-

Find similar trials in Philadelphia, PA

By condition
Atopic dermatitis / eczema
By specialty
DermatologyRheumatologyAutoimmune disease
By research site
The University of Pennsylvania· Philadelphia, PA

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