Multimodal Image Analysis and Guidance of Neuromodulation for Trauma-Related Symptoms

Part of paid clinical trials in Albuquerque, New Mexico.

Sponsor
University of New Mexico
Study ID
NCT06449326
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - 80 Years
Healthy Volunteers
Not accepted

Interventions

  • Active Intermittent theta burst stimulation — DEVICE
    Intermittent theta burst stimulation (iTBS) is an efficient form of transcranial magnetic stimulation that allows up to 10x more pulses to be delivered in a given timeframe compared to conventional stimulation patterns.
  • Sham Intermittent theta burst stimulation — DEVICE
    Intermittent theta burst stimulation (iTBS) is an efficient form of transcranial magnetic stimulation that allows up to 10x more pulses to be delivered in a given timeframe compared to conventional stimulation patterns.

Study Details

MAGNETS is a prospective, randomized, parallel-design, sham-controlled clinical trial of accelerated, functional magnetic resonance imaging (fMRI)-guided intermittent theta burst stimulation (iTBS) to the right dorsolateral prefrontal cortex (dlPFC) for chronic symptoms of posttraumatic stress disorder (PTSD) in a comorbid Veteran population.

Key Dates

Start date
Jun 1, 2024
Status verified
Jul 2025
Primary completion
Oct 1, 2027
Completion
Oct 1, 2027

Study Design

Enrollment
64 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Active iTBS
    Participants in this arm will undergo 50 sessions of active accelerated (10x/day, five days) image-guided iTBS.
  • Sham Comparator: Sham iTBS
    Participants in this arm will undergo 50 sessions of sham accelerated (10x/day, five days) image-guided iTBS.

Primary Outcome Measure

CAPS-5 [ Time Frame: Immediate post-treatment visit ]

Central Contacts

Locations (2)

FacilityCityStateZIPSite coordinators
New Mexico VA Health Care SystemAlbuquerqueNew Mexico87108
Tiana Maple
505-265-1711
UNM Center for Psychiatric ResearchAlbuquerqueNew Mexico87106
Davin Quinn, MD
[email protected]
505-272-9494
Davin Quinn, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Albuquerque, NM

By condition
PTSD (post-traumatic stress disorder)
By specialty
PsychiatryMental healthBehavioral health
By research site
New Mexico VA Health Care System· Albuquerque, NMUNM Center for Psychiatric Research· Albuquerque, NM

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