Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder

Part of paid clinical trials in New Haven, Connecticut.

Sponsor
Yale University
Study ID
NCT06446765
Phase
PHASE2
Status
Recruiting
Apply to this trial

Conditions

  • Borderline Personality Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - 60 Years
Healthy Volunteers
Not accepted

Interventions

  • mindfulness-based Neurofeedback — BEHAVIORAL
    Participants will complete one session of mindfulness-based fMRI neurofeedback prior to 20 weeks of remote online weekly DBT skills group.
  • control Neurofeedback — OTHER
    Participants will complete one session of control fMRI neurofeedback prior to 20 weeks of remote online weekly DBT skills group.

Study Details

The purpose of this study is to test the ability of mindfulness-based real time functional magnetic resonance imaging (fMRI) neurofeedback (mbNF) to increase the benefits of evidence-based psychotherapy for adults with Borderline Personality Disorder (BPD).

Key Dates

Start date
Mar 13, 2025
Status verified
Jun 2026
Primary completion
Oct 30, 2026
Completion
Oct 30, 2026

Study Design

Enrollment
150 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: mindfulness-based Neurofeedback
    Participants will participate in one session of mindfulness-based fMRI neurofeedback followed by 20 weeks of remote online weekly Dialectical Behavior Therapy skills group.
  • Other: control Neurofeedback
    Participants will participate in one session of control fMRI neurofeedback followed by 20 weeks of remote online weekly Dialectical Behavior Therapy skills group.

Primary Outcome Measure

Change in within-Default Mode Network (DMN) resting state functional connectivity after one session of neurofeedback (NF) [ Time Frame: From baseline (immediately before neurofeedback) to immediately after neurofeedback on the same day ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Connecticut Mental Health CenterNew HavenConnecticut06519
Sarah K Fineberg, MD/PhD
[email protected]
203-974-7265

Find similar trials in New Haven, CT

By research site
Connecticut Mental Health Center· New Haven, CT

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