Protest Trial: TXA vs Saline

Part of paid clinical trials in Grand Rapids, Michigan.

Sponsor
Corewell Health West
Study ID
NCT06422273
Phase
PHASE3
Status
Enrolling By Invitation

Conditions

  • Complications Surgical
  • Lung Transplant

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Tranexamic Acid — DRUG
    Endobronchial (topical) tranexamic acid used prophylactically prior to performing transbronchial biopsies in lung transplant recipients
  • Saline (placebo) — OTHER
    Topical Saline (placebo) administered as endobronchial topical application prior to performing transbronchial biopsies in lung transplant recipients.

Study Details

To determine if endobronchial (topical) tranexamic acid used prophylactically prior to performing transbronchial biopsies in lung transplant recipients reduces bleeding risk.

Key Dates

Start date
Apr 16, 2024
Status verified
Jan 2026
Primary completion
Jun 30, 2026
Completion
Jun 30, 2027

Study Design

Enrollment
94 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION

Arms

  • Experimental: TXA
    Tranexamic acid used prophylactically prior to performing transbronchial biopsies in lung transplant recipients.
  • Placebo Comparator: Saline
    Topical Saline (placebo) administered as endobronchial topical application.

Primary Outcome Measure

Bleeding Risk [ Time Frame: up to 1 hour ]

Locations (1)

FacilityCityStateZIPSite coordinators
Corewell Health WestGrand RapidsMichigan49503-

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Corewell Health West· Grand Rapids, MI

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