Adjuvant Therapy With Letrozole in Induction of Ovulation With Polycystic Ovarian Syndrome

Sponsor
Beni-Suef University
Study ID
NCT06405178
Phase
PHASE3
Status
Completed

Conditions

  • Polycystic Ovary

Eligibility Criteria

Sex
FEMALE
Age
20 Years - 40 Years
Healthy Volunteers
Not accepted

Interventions

Study Details

The aim of the study is to assess the efficacy of adjuvant therapy dapagliflozin, metformin as monotherapy and combination of both in comparison to control group in induction of ovulation with letrozole in women PCOS, focusing specifically on rates of ovulation and pregnancy.

Key Dates

Start date
Mar 30, 2026
Status verified
May 2026
Primary completion
Mar 30, 2026
Completion
Apr 1, 2026

Study Design

Enrollment
200 participants (actual)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Metformin 1000mg
  • Experimental: Dapagliflozin 10mg
  • Experimental: Dapagliflozin-Metformin 10/1000mg
  • No Intervention: control group.

Primary Outcome Measure

Pregnancy [ Time Frame: 3 cycles ( 3 months / one month for each cycle) ]

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