Wisconsin Ginseng for Decreasing Cancer Related Fatigue

Part of paid clinical trials in Albert Lea, Minnesota.

Sponsor
Mayo Clinic
Study ID
NCT06395441
Phase
PHASE3
Status
Recruiting
Apply to this trial

Conditions

  • Malignant Solid Neoplasm

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • American Ginseng — DIETARY_SUPPLEMENT
    Given PO
  • Placebo Administration — DRUG
    Given PO
  • Questionnaire Administration — OTHER
    Ancillary studies

Study Details

This phase III trial compares the effect of Wisconsin ginseng (panax quinquefolius) to placebo in patients with cancer that suffer from significant fatigue. Fatigue is among the most challenging symptoms to manage in patients with cancer, both on or off active treatment. This symptom complex meaningfully contributes to psychosocial distress, healthcare costs, and it also interferes with the delivery of anticancer therapies. American ginseng (Western ginseng) appears to be a promising appearing agent for treating cancer related fatigue. Western ginseng may reduce cancer-related fatigue.

Key Dates

Start date
Aug 1, 2024
Status verified
Mar 2026
Primary completion
Nov 30, 2026
Completion
Nov 30, 2026

Study Design

Enrollment
160 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE

Arms

  • Experimental: Group I (Western ginseng)
    Patients receive Western ginseng PO BID on days 1-56. Treatment continues in the absence of disease progression or unacceptable toxicity.
  • Placebo Comparator: Group II (placebo)
    Patients receive placebo PO BID on days 1-56. Treatment continues in the absence of disease progression or unacceptable toxicity.

Primary Outcome Measure

Change in fatigue [ Time Frame: Baseline to 8 weeks ]

Central Contacts

Locations (15)

FacilityCityStateZIPSite coordinators
Mayo Clinic Health System in Albert LeaAlbert LeaMinnesota56007
Clinical Trials Referral Office
[email protected]
855-776-0015
Danielle Mutschler
[email protected]
507-377-4817
Mina Hanna, MD (PRINCIPAL_INVESTIGATOR)
Sanford Joe Lueken Cancer CenterBemidjiMinnesota56601
Jarrett Failing, MD
[email protected]
612-624-2620
Jarrett Failing, MD (PRINCIPAL_INVESTIGATOR)
Essentia Health Saint Joseph's Medical CenterBrainerdMinnesota56401
Bret Friday, MD
[email protected]
612-624-2620
Bret Friday, MD (PRINCIPAL_INVESTIGATOR)
Essentia Health Deer River ClinicDeer RiverMinnesota56636
Bret Friday, MD
[email protected]
612-624-2620
Bret Friday, MD (PRINCIPAL_INVESTIGATOR)
Essentia Health St. Mary's Detroit Lakes ClinicDetroit LakesMinnesota56501
Bret Friday, MD
[email protected]
612-624-2620
Bret Friday, MD (PRINCIPAL_INVESTIGATOR)
Essentia Health Cancer CenterDuluthMinnesota55805
Bret Friday, MD
[email protected]
218-786-3625
Bret Friday, MD (PRINCIPAL_INVESTIGATOR)
Essentia Health FosstonFosstonMinnesota56542
Bret Friday, MD
[email protected]
612-624-2620
Bret 1 Friday, MD (PRINCIPAL_INVESTIGATOR)
Essentia Health Hibbing ClinicHibbingMinnesota55746
Bret Friday, MD
[email protected]
612-624-2620
Bret Friday, MD (PRINCIPAL_INVESTIGATOR)
Mayo Clinic Health System-MankatoMankatoMinnesota56001
Clinical Trials Referral Office
[email protected]
855-776-0015
Jenna Ziegler
[email protected]
507-594-7479
Stephan Thome, MD (PRINCIPAL_INVESTIGATOR)
MMCORC CentraCare Monticello Cancer CenterMonticelloMinnesota55362-
Mayo Clinic in RochesterRochesterMinnesota55905
Clinical Trials Referral Office
[email protected]
855-776-0015
Daniel S. Childs, M.D. (PRINCIPAL_INVESTIGATOR)
Stacy D. D'Andre, M.D. (PRINCIPAL_INVESTIGATOR)
Essentia Health SandstoneSandstoneMinnesota55072
Bret Friday, MD
[email protected]
612-624-2620
Bret Friday, MD (PRINCIPAL_INVESTIGATOR)
Sanford Thief River Falls Medical CenterThief River FallsMinnesota56701
Amit Panwalkar, MD
[email protected]
612-624-2620
Amit Panwalkar, MD (PRINCIPAL_INVESTIGATOR)
Essentia Health Virginia ClinicVirginiaMinnesota55792
Bret Friday, MD
[email protected]
612-624-2620
Bret Friday, MD (PRINCIPAL_INVESTIGATOR)
Sanford Worthington Medical CenterWorthingtonMinnesota56187
Jonathan Bleeker, MD
[email protected]
Jonathan Bleeker, MD (PRINCIPAL_INVESTIGATOR)

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