The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis
- Sponsor
- Shanghai Zhongshan Hospital
- Study ID
- NCT06393972
- Phase
- PHASE2
- Status
- Not Yet Recruiting
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Conditions
- Glucocorticoid Resistant ICIs-related Myocarditis
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 85 Years
- Healthy Volunteers
- Not accepted
Interventions
- Tofacitinib 5 MG BID — DRUGTofacitinib 5 MG BID
Study Details
The efficacy and safety of Tofacitinib in patients with glucocorticoid resistant ICIs-related myocarditis: a single-arm, prospective, phase 2 trial
Key Dates
- Start date
- Jul 1, 2024
- Status verified
- Apr 2024
- Primary completion
- Nov 30, 2025
- Completion
- Nov 30, 2026
Study Design
- Enrollment
- 25 participants (estimated)
- Allocation
- NA
- Intervention model
- SINGLE_GROUP
- Primary purpose
- TREATMENT
Arms
- Experimental: TofacitinibTofacitinib in patients with glucocorticoid resistant ICIs-related myocarditis
Primary Outcome Measure
All-cause mortality within three months [ Time Frame: The first three months after tofacitinib administration ]
Central Contacts
- Yan Wang+86-21-64041990