Post Pandemic Pneumococcal Carriage Among Children and Adults

Conditions

• Pneumococcal Carriage

Eligibility Criteria

Sex

ALL

Age

7 Months - N/A

Healthy Volunteers

Accepted

Study Details

The PI propose to conduct a genomic epidemiology study of pneumococcal carriage among children and adults in a large metropolitan city. These data will allow PI to assess the post-pandemic population structure, investigate the phylogenetic relationship between isolates from children and adults, and compare pneumococcal populations across diverse geographic areas.

Key Dates

Start date

Jun 12, 2024

Status verified

Dec 2024

Primary completion

Sep 30, 2025

Completion

Mar 31, 2026

Study Design

Enrollment

900 participants (estimated)

Arms

• Arm: Children
  This is a non-interventional study with data collection online, chart review, and biospecimen collection (nasopharyngeal swab). The swab will then be used for biomarker discovery. Findings will be compared and analyzed between the children and adult groups.
• Arm: Adults
  This is a non-interventional study with data collection online, chart review, and biospecimen collection (nasopharyngeal swab). The swab will then be used for biomarker discovery. Findings will be compared and analyzed between the children and adult groups.

Primary Outcome Measure

Pneumococcal carriage prevalence and distribution of serotypes among children and adults calculated from the results of S. pneumoniae isolation using qPCR. [ Time Frame: 22 months ]

Central Contacts

• Amoy Fraser, PhD, CCRP, PMP
  4072668742
  [email protected]
• Erica Martin, B.S.
  4072668742
  [email protected]

Locations (1)

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