The Acute T-Rex (Timing of Resistance Exercise) Study

Part of paid clinical trials in Salt Lake City, Utah.

Sponsor
University of Utah
Study ID
NCT06366399
Status
Recruiting

Conditions

Eligibility Criteria

Sex
ALL
Age
50 Years - 74 Years
Healthy Volunteers
Not accepted

Interventions

  • Resistance Exercise Timing — BEHAVIORAL
    1 resistance exercise session consisting of 3 sets, 10 repetitions per set, on 12 different exercises

Study Details

The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laboratory setting. Each condition will consist of exercise, overnight sleep, and oral glucose tolerance tests the following day. The AM exercise will occur \~1.5 hours after habitual wake, and PM exercise will occur \~11 hours after habitual wake. After a 2-6 week washout, participants will complete the other condition. The hypothesis is that PM exercise will be more beneficial than AM exercise in improving insulin sensitivity. This study could identify if there is a better time of day to perform resistance exercise to decrease risk of developing Type 2 Diabetes Mellitus.

Key Dates

Start date
Nov 15, 2023
Status verified
Mar 2025
Primary completion
Dec 31, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
20 participants (estimated)
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION

Arms

  • Experimental: AM Resistance Exercise
    Resistance Exercise intervention taking place in the AM
  • Experimental: PM Resistance Exercise
    Resistance Exercise intervention taking place in the PM

Primary Outcome Measure

Insulin sensitivity [ Time Frame: 1 day ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of Utah HPER E BuildlingSalt Lake CityUtah84112
Jason V Thomas, MS
Tanya M Halliday, PhD (PRINCIPAL_INVESTIGATOR)

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