Impact of Sex in the Effect of Dietary Capsaicin on Cardiovascular Health

Part of paid clinical trials in Saratoga Springs, New York.

Sponsor
Skidmore College
Study ID
NCT06363305
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • Dietary capsules — DIETARY_SUPPLEMENT
    Daily doses of dietary capsaicin or placebo in capsule form

Study Details

The investigators long-term goal is to better understand novel interventions to promote cardiovascular health in humans. The goal of the proposed research is to investigate whether there is sex-specificity in the effects of dietary capsaicin on mechanisms regulating nitric oxide (NO) bioavailability, its effect on key markers of cardiovascular (CV) health, including BP, macro- and microvascular function, and arterial stiffness. This knowledge will provide critical insight into the effects of dietary capsaicin on CV health and will guide future trials.

Key Dates

Start date
Jul 8, 2024
Status verified
Jul 2024
Primary completion
Dec 1, 2025
Completion
Dec 31, 2025

Study Design

Enrollment
80 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE

Arms

  • Experimental: Dietary Capsaicin
    Over-the-counter dose of 2 x 440 mg capsules (880 mg, Capsicum Pepper Blend, Daily Manufacturing, Rockwell, North Carolina, USA)
  • Placebo Comparator: Placebo
    The placebo will be 2 x 400-500 mg fiber (800 mg psyllium husk) capsules which were chosen to be of similar appearance (size, coloration, and texture).

Primary Outcome Measure

Blood Pressure and Vascular Stiffness [ Time Frame: Baseline, 24 hours, and 6-weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Skidmore CollegeSaratoga SpringsNew York12866
Stephen Ives, Ph.D.
[email protected]
518-580-8366

Find similar trials in Saratoga Springs, NY

By condition
Hypertension (high blood pressure)
By specialty
CardiologyHeart disease
By research site
Skidmore College· Saratoga Springs, NY

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