Fiber Supplementation in Heart Failure With Preserved Ejection Fraction (HFpEF)

Part of paid clinical trials in Ann Arbor, Michigan.

Sponsor
University of Michigan
Study ID
NCT06337812
Status
Recruiting
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Conditions

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Potato Starch — DIETARY_SUPPLEMENT
    Participants will consume 10 grams (1/2 a packet) of Bob's Red Mill Potato Starch twice a day for the first 7 days and then increase to 20 grams (full packet) of potato starch for approximately 3 weeks. Potato starch can be mixed into cold food or beverage for consumption. In addition, participants will have evaluations and provide blood and stool samples during the study.

Study Details

The study team is studying how increasing dietary fiber, specifically through adding potato starch to participant's diet, may impact the species of bacteria in participant's gut microbiome. The study team also wants to understand if adding potato starch to participant's diet helps these bacteria make more short chain fatty acids, a byproduct the team thinks may benefit participant's health.

Key Dates

Start date
Apr 1, 2024
Status verified
Jul 2025
Primary completion
Jun 30, 2026
Completion
Dec 31, 2026

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH

Arms

  • Experimental: Potato starch supplement
    Participants will take the supplement for approximately 4 weeks.

Primary Outcome Measure

Changes in Short Chain Fatty Acid (SCFA) butyrate levels - stool [ Time Frame: Baseline, approximately 4 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
University of MichiganAnn ArborMichigan48109
Hayley Billingsley, PhD
[email protected]
734-726-0308
Scott Hummel, MD, MS (PRINCIPAL_INVESTIGATOR)

Find similar trials in Ann Arbor, MI

By condition
Heart failure
By specialty
CardiologyHeart disease
By research site
University of Michigan· Ann Arbor, MI

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